Quinoxaline synthesis from α-hydroxy ketones via a tandem oxidation process using catalysed aerobic oxidation

被引：203

作者：

Robinson, RS ^{[1
]}

Taylor, RJK ^{[1
]}

机构：

[1] Univ York, Dept Chem, York YO10 5DD, N Yorkshire, England

来源：

SYNLETT | 2005年 / 06期

关键词：

direct conversion; alpha-hydroxy ketones; quinoxalines;

D O I：

10.1055/s-2005-864830

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The direct conversion of alpha-hydroxy ketones into quinoxalines via metal-catalysed aerobic oxidation followed by in situ trapping with aromatic 1,2-diamines is reported. Catalyst screening indicated that these transformations could be carried out efficiently using 2 mol% Pd(OAc)(2) or RuCl2(PPh3)(3)-TEMPO; the palladium system was utilised for a range of transformations.

引用

页码：1003 / 1005

页数：3

共 17 条

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