Hammerhead ribozyme kinetics

被引：177

作者：

Stage-Zimmermann, TK ^{[1
]}

Uhlenbeck, OC ^{[1
]}

机构：

[1] Univ Colorado, Dept Chem & Biochem, Boulder, CO 80309 USA

来源：

RNA | 1998年 / 4卷 / 08期

关键词：

catalytic RNA; RNA conformations;

D O I：

10.1017/S1355838298980876

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

[No abstract available]

引用

页码：875 / 889

页数：15

共 107 条

[51] Similar cleavage efficiencies of an oligoribonucleotide substrate and an mdr1 mRNA segment by a hammerhead ribozyme [J].

Holm, PS ;

Dietel, M ;

Krupp, G .

GENE, 1995, 167 (1-2) :221-225

[52] EXTENSION OF HELIX-II OF AN HIV-1-DIRECTED HAMMERHEAD RIBOZYME WITH LONG ANTISENSE FLANKS DOES NOT ALTER KINETIC-PARAMETERS IN-VITRO BUT CAUSES LOSS OF THE INHIBITORY POTENTIAL IN LIVING CELLS [J].

HOMANN, M ;

TABLER, M ;

TZORTZAKAKI, S ;

SCZAKIEL, G .

NUCLEIC ACIDS RESEARCH, 1994, 22 (19) :3951-3957

[53] The subcellular localization and length of hammerhead ribozymes determine efficacy in human cells [J].

Hormes, R ;

Homann, M ;

Oelze, I ;

Marschall, P ;

Tabler, M ;

Eckstein, F ;

Sczakiel, G .

NUCLEIC ACIDS RESEARCH, 1997, 25 (04) :769-775

[54] SELF-CLEAVAGE OF PLUS AND MINUS RNA TRANSCRIPTS OF AVOCADO SUNBLOTCH VIROID [J].

HUTCHINS, CJ ;

RATHJEN, PD ;

FORSTER, AC ;

SYMONS, RH .

NUCLEIC ACIDS RESEARCH, 1986, 14 (09) :3627-3640

[55] Oligonucleotide facilitators may inhibit or activate a hammerhead ribozyme [J].

Jankowsky, E ;

Schwenzer, B .

NUCLEIC ACIDS RESEARCH, 1996, 24 (03) :423-429

[56] Peptide nucleic acid (PNA) is capable of enhancing hammerhead ribozyme activity with long but not with short RNA substrates [J].

Jankowsky, E ;

Strunk, G ;

Schwenzer, B .

NUCLEIC ACIDS RESEARCH, 1997, 25 (14) :2690-2693

[57] A CATALYTIC 13-MER RIBOZYME [J].

JEFFRIES, AC ;

SYMONS, RH .

NUCLEIC ACIDS RESEARCH, 1989, 17 (04) :1371-1377

[58] Constructing an efficient trans-acting genomic HDV ribozyme [J].

Kawakami, J ;

Yuda, K ;

Suh, YA ;

Kumar, PKR ;

Nishikawa, F ;

Maeda, H ;

Taira, K ;

Ohtsuka, E ;

Nishikawa, S .

FEBS LETTERS, 1996, 394 (02) :132-136

[59] CLEAVAGE OF SPECIFIC SITES OF RNA BY DESIGNED RIBOZYMES [J].

KOIZUMI, M ;

IWAI, S ;

OHTSUKA, E .

FEBS LETTERS, 1988, 239 (02) :285-288

[60] DESIGN OF RNA ENZYMES DISTINGUISHING A SINGLE BASE MUTATION IN RNA [J].

KOIZUMI, M ;

HAYASE, Y ;

IWAI, S ;

KAMIYA, H ;

INOUE, H ;

OHTSUKA, E .

NUCLEIC ACIDS RESEARCH, 1989, 17 (17) :7059-7071

← 1 2 3 4 5 6 7 8 9 10 →