Conjugated polymer-based fluorescence turn-on sensor for nitric oxide

被引：103

作者：

Smith, RC ^{[1
]}

Tennyson, AG ^{[1
]}

Lim, MH ^{[1
]}

Lippard, SJ ^{[1
]}

机构：

[1] MIT, Dept Chem, Cambridge, MA 02139 USA

来源：

ORGANIC LETTERS | 2005年 / 7卷 / 16期

关键词：

D O I：

10.1021/ol0513903

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A turn-on fluorescent sensor for NO (g) in solution was synthesized using a bipyridyl-substituted poly(p-phenylene vinylene) derivative (CP1) as the sensory scaffold. The action of NO (g) upon the CP1-Cu(II) complex reduces it to the CP1-Cu(l) complex with a concomitant 2.8-fold increase in emission intensity. The reagent is selective for NO (g) versus other biological reactive nitrogen species, except for nitroxyl, and has a detection sensitivity limit of 6.3 nM.

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页码：3573 / 3575

页数：3

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