Application of eVOC: controlled vocabularies for unifying gene expression data

被引:3
作者
Hide, W [1 ]
Smedley, D
McCarthy, M
Kelso, J
机构
[1] Univ Western Cape, S African Natl Bioinformat Inst, ZA-7535 Bellville, South Africa
[2] Oxford Ctr Diabet Endocrinol & Metab, Oxford OX3 7LJ, England
[3] Wellcome Trust Ctr Human Genet, Oxford OX3 7LJ, England
基金
新加坡国家研究基金会; 英国惠康基金;
关键词
controlled vocabulary; EnsMart; EST; gene expression; microarray; ontology; SAGE;
D O I
10.1016/j.crvi.2003.09.030
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
To provide standardised description of gene expression and cross platform querying of databases, we have developed eVOC (http://www.sanbi.ac.za/evoc/), consisting of four orthogonal ontologies which describe Anatomical System, Cell Type, Pathology and Developmental Stage. We have annotated 47 microarray expression data sets and all publicly available human cDNA and SAGE tag libraries. eVOC has been integrated with the public resource EnsMart, which provides linking of transcripts and libraries with expression terms and the human genome sequence (http://www.ensembl.org/Homo_sapiens/martview). (C) 2003 Published by Elsevier SAS on behalf of Academie des sciences.
引用
收藏
页码:1089 / 1096
页数:8
相关论文
共 9 条
  • [1] Ashburner M, 2001, GENOME RES, V11, P1425
  • [2] Gene Ontology: tool for the unification of biology
    Ashburner, M
    Ball, CA
    Blake, JA
    Botstein, D
    Butler, H
    Cherry, JM
    Davis, AP
    Dolinski, K
    Dwight, SS
    Eppig, JT
    Harris, MA
    Hill, DP
    Issel-Tarver, L
    Kasarskis, A
    Lewis, S
    Matese, JC
    Richardson, JE
    Ringwald, M
    Rubin, GM
    Sherlock, G
    [J]. NATURE GENETICS, 2000, 25 (01) : 25 - 29
  • [3] GRAY HL, 1995, GRAYS ANATOMY, V38
  • [4] The KEGG databases at GenomeNet
    Kanehisa, M
    Goto, S
    Kawashima, S
    Nakaya, A
    [J]. NUCLEIC ACIDS RESEARCH, 2002, 30 (01) : 42 - 46
  • [5] The EcoCyc database
    Karp, PD
    Riley, M
    Saier, M
    Paulsen, IT
    Collado-Vides, J
    Paley, SM
    Pellegrini-Toole, A
    Bonavides, C
    Gama-Castro, S
    [J]. NUCLEIC ACIDS RESEARCH, 2002, 30 (01) : 56 - 58
  • [6] The MetaCyc database
    Karp, PD
    Riley, M
    Paley, SM
    Pellegrini-Toole, A
    [J]. NUCLEIC ACIDS RESEARCH, 2002, 30 (01) : 59 - 61
  • [7] RECTOR AL, 2001, K CAP 01, P139
  • [8] TAMBIS: Transparent access to multiple bioinformatics information sources
    Stevens, R
    Baker, P
    Bechhofer, S
    Ng, G
    Jacoby, A
    Paton, NW
    Goble, CA
    Brass, A
    [J]. BIOINFORMATICS, 2000, 16 (02) : 184 - 185
  • [9] Mutations in a novel retina-specific gene cause autosomal dominant retinitis pigmentosa
    Sullivan, LS
    Heckenlively, JR
    Bowne, SJ
    Zuo, J
    Hide, WA
    Gal, A
    Denton, M
    Inglehearn, CF
    Blanton, SH
    Daiger, SP
    [J]. NATURE GENETICS, 1999, 22 (03) : 255 - 259