High enantiocontrol in the intramolecular cyclopropanation of diazo ketones catalyzed by dirhodium(II) complexes with ortho-metalated aryl phosphine ligands

被引：44

作者：

Barberis, M ^{[1
]}

Pérez-Prieto, J

Stiriba, SE

Lahuerta, P

机构：

[1] Univ Valencia, Fac Farm, Inst Ciencia Mol, Dept Quim Organ, E-46100 Burjassot, Valencia, Spain

[2] Univ Valencia, Fac Farm, Dept Quim Inorgan, E-46100 Burjassot, Valencia, Spain

来源：

ORGANIC LETTERS | 2001年 / 3卷 / 21期

关键词：

D O I：

10.1021/ol010170w

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] Chiral dirhodium(II) complexes, Rh-2(O2CCF3)(2)(PC)(2), [PCH = (p-CH3C6H4)(3)P, (m-CH3C6H4)(3)P], provide an excellent yield and a high enantiocontrol in the cyclopropanation of alpha -diazo ketones with gamma and delta double bonds. The ee values are significantly dependent on the solvent used the best results are obtained using pentane.

引用

页码：3317 / 3319

页数：3

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