Recent Advances in Wearable Transdermal Delivery Systems

被引：183

作者：

Amjadi, Morteza ^{[1
,2
]}

Sheykhansari, Sahar ^{[1
]}

Nelson, Bradley J. ^{[2
]}

Sitti, Metin ^{[1
]}

机构：

[1] Max Planck Inst Intelligent Syst, Phys Intelligence Dept, D-70569 Stuttgart, Germany

[2] ETH, Dept Mech & Proc Engn, CH-8092 Zurich, Switzerland

来源：

ADVANCED MATERIALS | 2018年 / 30卷 / 07期

关键词：

drug carriers; multifunctional wearable devices; stimuli-responsive materials; transdermal delivery; wearable medical systems; FORMING MICRONEEDLE ARRAYS; REDUCED GRAPHENE OXIDE; DRUG-DELIVERY; PRESSURE SENSORS; RESPONSIVE NANOCARRIERS; COMPOSITE MICRONEEDLES; NONINVASIVE DELIVERY; POLYMER MICRONEEDLES; SENSITIVE VESICLES; TEMPERATURE-SENSOR;

D O I：

10.1002/adma.201704530

中图分类号：

O6 [化学];

学科分类号：

070301 [无机化学];

摘要：

Wearable transdermal delivery systems have recently received tremendous attention due to their noninvasive, convenient, and prolonged administration of pharmacological agents. Here, the material prospects, fabrication processes, and drug-release mechanisms of these types of therapeutic delivery systems are critically reviewed. The latest progress in the development of multifunctional wearable devices capable of closed-loop sensation and drug delivery is also discussed. This survey reveals that wearable transdermal delivery has already made an impact in diverse healthcare applications, while several grand challenges remain.

引用

页数：19

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