New hirsutane based sesquiterpenes from salt water cultures of a marine sponge-derived fungus and the terrestrial fungus Coriolus consors

被引：59

作者：

Wang, GYS ^{[1
]}

Abrell, LM ^{[1
]}

Avelar, A ^{[1
]}

Borgeson, BM ^{[1
]}

Crews, P ^{[1
]}

机构：

[1] Univ Calif Santa Cruz, Dept Chem & Biochem, Santa Cruz, CA 95064 USA

来源：

TETRAHEDRON | 1998年 / 54卷 / 26期

基金：

美国海洋和大气管理局; 美国国家卫生研究院; 美国国家科学基金会;

关键词：

D O I：

10.1016/S0040-4020(98)00398-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Five new cyclic sesquiterpenes, hirsutanols A (6), B (7), C (8), hirsutanol D (9), and ent-gloeosteretriol (10) and a new diketopiperazine (14) were isolated from salt water cultures of two fungi. Sesquiterpenes 6 - 8 and 10 were obtained fi om an unidentified fungus separated from an Indo-Pacific sponge Haliclona sp. while 9 and 14 were produced by the terrestrial fungus Coriolus censors cultured under both sea water and deionized water media. Hirsutanol A (6) and ent-gloeosteretriol (10) were found to be anti-microbial (Bacillus subtilus) active. All structures were elucidated by spectroscopic methods. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：7335 / 7342

页数：8

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