New method for the combinatorial search of multi component reactions

被引：36

作者：

Mironov, MA ^{[1
]}

Mokrushin, VS ^{[1
]}

Maltsev, SS ^{[1
]}

机构：

[1] Urals State Tech Univ, Dept Technol Organ Synth, TOSLab, Ekaterinburg 620002, Russia

来源：

SYNLETT | 2003年 / 07期

关键词：

multi component reaction; isocyanides; isoquinoline; reaction design; combinatorial chemistry;

D O I：

10.1055/s-2003-39298

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel method for the combinatorial finding of multi component reactions involving replacements of oligomerisation participants is introduced. Using this method the new three-component reaction between isoquinoline, gem-diactivated olefins and isocyanides leading to substituted 2,3-dihydro-10H-pyrrolo[2,1-a]isoquinoline-1-ones is described.

引用

页码：943 / 946

页数：4

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