Cancer and gene therapy

被引:14
作者
SchmidtWolf, GD [1 ]
SchmidtWolf, IGH [1 ]
机构
[1] HUMBOLDT UNIV BERLIN,VIRCHOW CLIN,DEPT INTERNAL MED,DIV HEMATOL ONCOL,D-13353 BERLIN,GERMANY
关键词
cancer; gene therapy; gene transfer; review;
D O I
10.1007/s002770050231
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The authors review the current literature pertaining to gene therapy as related to human cancer, covering gene therapy strategies, techniques of gene transfer, and targeted gene delivery. Gene therapy has various applications. Many technical obstacles in gene delivery need to be overcome. The safe delivery and expression of a gene to its destination are essential for clinical use. A greater understanding of the genetic basis of cancer and tumor immunology is necessary before the goal of cancer gene therapy can be fully realized.
引用
收藏
页码:207 / 218
页数:12
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