Recent trends in antibody based sensors

被引：215

作者：

Holford, Timothy R. J. ^{[1
]}

Davis, Frank ^{[1
]}

Higson, Seamus P. J. ^{[1
]}

机构：

[1] Cranfield Univ, Cranfield Hlth, Cranfield MK43 0AL, Beds, England

来源：

BIOSENSORS & BIOELECTRONICS | 2012年 / 34卷 / 01期

基金：

英国工程与自然科学研究理事会;

关键词：

Immunosensor; Point of care; Lab on a chip; Reusable; Continuous monitoring; SURFACE-PLASMON RESONANCE; LABELESS IMMUNOSENSOR ASSAY; QUARTZ-CRYSTAL MICROBALANCE; LINKED-IMMUNOSORBENT-ASSAY; OPTICAL-FIBER IMMUNOSENSOR; STROKE MARKER PROTEIN; ELECTROCHEMICAL DETECTION; GOLD NANOPARTICLES; ALPHA-FETOPROTEIN; CARBON NANOTUBES;

D O I：

10.1016/j.bios.2011.10.023

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

This review details recent advances in the fields of immunosensors and closely related immunoassays in the past decade, together with a discussion of possible future trends. Immunosensors can be classified by the way in which they transduce the signal produced upon the formation of an antibody antigen complex. Recent advancements to these methods of detection and transduction are discussed in detail, with particular focus on electrochemical, optical, piezoelectric and magnetic based sensors. The varying applications of these sensors are also discussed. Some of the most significant advances include development of immunosensors for the continuous monitoring of analytes, point of care (PoC) devices, with lower unit costs, automation, reusability and ease of use. Immunosensor technology has advanced at a prolific rate since its conception and has grown into a diverse area of ongoing research. (C) 2012 Published by Elsevier B.V.

引用

页码：12 / 24

页数：13

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