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Genetics of lipoprotein disorders

被引：67
作者：
Davignon, J
Genest, J
机构：
[1] Clin Res Inst Montreal, Hyperlipidemia & Atherosclerosis Res Grp, Montreal, PQ H2W 1R7, Canada
[2] Clin Res Inst Montreal, Cardiovasc Genet Lab, Montreal, PQ H2W 1R7, Canada
[3] Univ Montreal, Fac Med, Montreal, PQ H3C 3J7, Canada
[4] Montreal Univ Hosp, Med Ctr, Dept Med, Montreal, PQ, Canada
来源：
ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA | 1998年 / 27卷 / 03期
关键词：
D O I：
10.1016/S0889-8529(05)70024-4
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Many genes intervene in the homeostasis of plasma lipoprotein concentrations, which are also sensitive to environmental changes. Although many inherited disorders of lipoprotein metabolism are recognized, the genetic defect is known for only a few. For practical reasons, and until the genetic etiology is fully elucidated, it is best to classify these defects as a function of their major lipoprotein phenotype. Because of the life-threatening potential of some of these disorders, emphasis is placed on the atherogenic forms of dyslipoproteinemias.
引用
收藏
页码：521 / +
页数：32
相关论文
共 247 条
  • [121] GENOTYPE AT A MAJOR LOCUS WITH LARGE EFFECTS ON APOLIPOPROTEIN-B LEVELS PREDICTS FAMILIAL COMBINED HYPERLIPIDEMIA
    JARVIK, GP
    BEATY, TH
    GALLAGHER, PR
    COATES, PM
    CORTNER, JA
    [J]. GENETIC EPIDEMIOLOGY, 1993, 10 (04) : 257 - 270
  • [122] Jensen HK, 1996, CLIN CHEM, V42, P1140
  • [123] KANE JP, 1995, METABOLIC MOL BASES, P1872
  • [124] LOW-DENSITY LIPOPROTEIN METABOLISM IN FAMILIAL COMBINED HYPERLIPIDEMIA - MECHANISM OF THE MULTIPLE LIPOPROTEIN PHENOTYPIC-EXPRESSION
    KISSEBAH, AH
    ALFARSI, S
    EVANS, DJ
    [J]. ARTERIOSCLEROSIS, 1984, 4 (06): : 614 - 624
  • [125] HETEROGENEITY OF LIPOPROTEIN (A) - GROWING COMPLEXITIES
    KLEZOVITCH, O
    SCANU, AM
    [J]. CURRENT OPINION IN LIPIDOLOGY, 1995, 6 (04) : 223 - 228
  • [126] KOIVISTO UM, 1993, J LIPID RES, V34, P269
  • [127] PHENOTYPIC-EXPRESSION AND FREQUENCY OF FAMILIAL DEFECTIVE APOLIPOPROTEIN B-100 IN BELGIAN HYPERCHOLESTEROLEMICS
    KOTZE, MJ
    PEETERS, AV
    LANGENHOVEN, E
    WAUTERS, JG
    VANGAAL, LF
    [J]. ATHEROSCLEROSIS, 1994, 111 (02) : 217 - 225
  • [128] PHENOTYPIC VARIATION AMONG FAMILIAL HYPERCHOLESTEROLEMICS HETEROZYGOUS FOR EITHER ONE OF 2 AFRIKANER FOUNDER LDL RECEPTOR MUTATIONS
    KOTZE, MJ
    DEVILLIERS, WJS
    STEYN, K
    KRIEK, JA
    MARAIS, AD
    LANGENHOVEN, E
    HERBERT, JS
    VANROGGEN, JFG
    VANDERWESTHUYZEN, DR
    COETZEE, GA
    [J]. ARTERIOSCLEROSIS AND THROMBOSIS, 1993, 13 (10): : 1460 - 1468
  • [129] Krauss Ronald M., 1994, Current Opinion in Lipidology, V5, P339, DOI 10.1097/00041433-199410000-00005
  • [130] Lipoprotein(a) in health and disease
    Kronenberg, F
    Steinmetz, A
    Kostner, GM
    Dieplinger, H
    [J]. CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES, 1996, 33 (06) : 495 - 543
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