Cell-cycle-dependent translational control

被引：155

作者：

Pyronnet, S

Sonenberg, N

机构：

[1] McGill Univ, Dept Biochem, Montreal, PQ H3G 1Y6, Canada

[2] McGill Univ, McGill Canc Ctr, Montreal, PQ H3G 1Y6, Canada

[3] CHU Rangueil, Inst Louis Bugnard, INSERM, U531, F-31403 Toulouse, France

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 2001年 / 11卷 / 01期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1016/S0959-437X(00)00150-7

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Control of translation in eukaryotes occurs mainly at the initiation step. Translation rates in mammals are robust in the G(1) phase of the cell cycle but are low during mitosis. These changes correlate with the activity of several canonical translation initiation factors, which is modulated during the cell cycle to regulate translation.

引用

页码：13 / 18

页数：6

共 59 条

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