Synthesis and structure determination of iso-cladospolide B

被引：38

作者：

Franck, X ^{[1
]}

Araujo, MEV ^{[1
]}

Jullian, JC ^{[1
]}

Hocquemiller, R ^{[1
]}

Figadère, B ^{[1
]}

机构：

[1] Univ Paris Sud, Fac Pharm, BIOCIS, CNRS,Lab Pharmacognosie, F-92296 Chatenay Malabry, France

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 15期

关键词：

polyketides; marine fungi; asymmetric aldol reaction; structure determination;

D O I：

10.1016/S0040-4039(01)00323-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

iso-Cladospolide B 1 was previously characterized from the fungal isolate I96S215 obtained from a marine sponge collected in Indonesia. However, neither the relative nor the absolute configurations were reported. We describe in this letter a synthetic pathway which allowed us to prepare 1 and attribute the absolute configurations of the three stereogenic centers. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：2801 / 2803

页数：3

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