A polymorphic CA repeat sequence at the human calcitonin locus

被引：13

作者：

Tsukamoto, K ^{[1
]}

Emi, M ^{[1
]}

机构：

[1] Nippon Med Sch, Inst Gerontol, Dept Biol Mol, Nakahara Ku, Kawasaki, Kanagawa 211, Japan

来源：

JOURNAL OF HUMAN GENETICS | 1998年 / 43卷 / 02期

关键词：

CA repeat; calcitonin gene; calcium metabolism; osteoporosis; hyperparathyroidism;

D O I：

10.1007/s100380050058

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

A polymorphic dinucleotide (CA) repeat sequence was isolated from a genomic clone containing the human calcitonin gene at 11p15.2-p15.1. This polymorphism will be a useful marker in the genetic study of disorders affecting calcium metabolism including hyperparathyroidism, hypoparathyroidism, and osteoporosis.

引用

页码：146 / 147

页数：2

共 7 条

[1] ALTERED CALCITONIN GENE IN A YOUNG PATIENT WITH OSTEOPOROSIS
ALEVIZAKI, M
STEVENSON, JC
GIRGIS, SI
MACINTYRE, I
LEGON, S
[J]. BRITISH MEDICAL JOURNAL, 1989, 298 (6682) : 1215 - 1216
[2] HIGH-RESOLUTION CHROMOSOMAL LOCALIZATION OF THE HUMAN CALCITONIN CGRP/IAPP GENE FAMILY MEMBERS
HOOVERS, JMN
REDEKER, E
SPELEMAN, F
HOPPENER, JWM
BHOLA, S
BLIEK, J
VANROY, N
LESCHOT, NJ
WESTERVELD, A
MANNENS, M
[J]. GENOMICS, 1993, 15 (03) : 525 - 529
[3] CALCITONIN MESSENGER-RNA ENCODES MULTIPLE POLYPEPTIDES IN A SINGLE PRECURSOR
JACOBS, JW
GOODMAN, RH
CHIN, WW
DEE, PC
HABENER, JF
[J]. SCIENCE, 1981, 213 (4506) : 457 - 459
[4] Application of DNA markers to clinical genetics
Nakamura, Y
[J]. JAPANESE JOURNAL OF HUMAN GENETICS, 1996, 41 (01): : 1 - 10
[5] 6 DINUCLEOTIDE REPEAT POLYMORPHISMS ON CHROMOSOME-7
NAKURA, J
MIKI, T
YE, L
MITSUDA, N
OGIHARA, T
OHTA, T
JINNO, Y
NIIKAWA, N
TAKAHASHIFUJII, A
ISHINO, Y
[J]. JAPANESE JOURNAL OF HUMAN GENETICS, 1994, 39 (04): : 447 - 449
[6] PRODUCTION OF A NOVEL NEUROPEPTIDE ENCODED BY THE CALCITONIN GENE VIA TISSUE-SPECIFIC RNA PROCESSING
ROSENFELD, MG
MERMOD, JJ
AMARA, SG
SWANSON, LW
SAWCHENKO, PE
RIVIER, J
VALE, WW
EVANS, RM
[J]. NATURE, 1983, 304 (5922) : 129 - 135
[7] Human genetics: Past, present, and future, with special reference to major trends in Japan
Yanase, T
[J]. JAPANESE JOURNAL OF HUMAN GENETICS, 1997, 42 (02) : 265 - 316

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