Information networks in the mammary gland

被引：355

作者：

Hennighausen, L ^{[1
]}

Robinson, GW ^{[1
]}

机构：

[1] NIDDK, Lab Genet & Physiol, NIH, Bethesda, MD 20892 USA

来源：

NATURE REVIEWS MOLECULAR CELL BIOLOGY | 2005年 / 6卷 / 09期

关键词：

D O I：

10.1038/nrm1714

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Unique developmental features during puberty, pregnancy, lactation and post-lactation make the mammary gland a prime object to explore genetic circuits that control the specification, proliferation, differentiation, survival and death of cells. Steroids and simple peptide hormones initiate and carry out complex developmental programmes, and reverse genetics has been used to define the underlying mechanistic connections.

引用

页码：715 / 725

页数：11

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