Six new dammarane-type triterpene saponins from leaves of Panax ginseng

Six new minor saponins, together with known ginsenosides, were isolated from the leaves of Panax ginseng. The new saponins were named as ginsenoside-Rh-5, -Rh-6, -Rh-7 -Rh-8, -Rb-9 and -Rg(7), and their structures were elucidated on the basis of chemical and physicochemical evidence to be as follows: ginsenaside-Rh-5,: 3 beta ,6 alpha ,12 beta ,24 xi -tetrahydroxy-dammar-20(22),25-diene 6-O-beta -glucopyranoside (1), -Rh-6: 3 beta ,6 alpha ,12 beta ,20(S)-tetrahydroxy-25-hydroperoxy-dammar-23-ene 20-O-beta -D-glucpyranoside (2), -Rh-7,: 3 beta ,7 beta ,12 beta ,200-tetrahydroxy-dammar-5,24-diene 20-O-beta -D-glucopyranoside (3), -Rh-8,: 3 beta ,6 alpha ,20(S)-trihydroxy-dammar-24-ene-12-one 20-O-beta -D-glucopyranoside (4), -Rh-9: 3 beta ,6 alpha ,20(S)-trihydroxy-12 beta ,23-epoxy-dammar-24-ene 20-O-beta -D-glucopyranoside (5) and -Rg(7),: 3-O-beta -D-glucopyranosyl 3 beta ,12 beta ,20(S),24(R)-tetrahydroxy-dammar 20-O-beta -glucopyranoside (6).