FeCl2-Catalyzed selective C-C bond formation by oxidative activation of a benzylic C-H bond

被引：335

作者：

Li, Zhiping ^{[1
]}

Cao, Lin

Li, Chao-Jun

机构：

[1] Renmin Univ China, Dept Chem, Beijing 100872, Peoples R China

[2] McGill Univ, Dept Chem, Montreal, PQ H3A 2K6, Canada

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2007年 / 46卷 / 34期

关键词：

C-H activation; cross-coupling; iron; peroxides redox; chemistry;

D O I：

10.1002/anie.200701782

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) Any old iron: Readily available and non-toxic FeCl2 effectively catalyzes C-C bond formation by oxidative activation of benzylic C-H bonds in the presence of tert-butyl peroxide as a stoichiometric oxidant (see scheme). The mild reaction conditions, good yields, low catalyst cost, and easy operation are the major advantages of this cross-dehydrogenation coupling reaction. © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：6505 / 6507

页数：3

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