Intramitochondrial recombination - is it why some mitochondrial genes sleep around?

被引：122

作者：

Dowton, M ^{[1
]}

Campbell, NJH

机构：

[1] Univ Wollongong, Inst Conservat Biol & Law, Dept Biol, Wollongong, NSW 2522, Australia

[2] Univ Queensland, Inst Mol Biosci, Dept Microbiol & Parasitol, Brisbane, Qld 4072, Australia

来源：

TRENDS IN ECOLOGY & EVOLUTION | 2001年 / 16卷 / 06期

基金：

澳大利亚研究理事会;

关键词：

D O I：

10.1016/S0169-5347(01)02182-6

中图分类号：

Q14 [生态学（生物生态学）];

学科分类号：

071012 ; 0713 ;

摘要：

A new paper by Kajander et al. undermines the general view that mitochondria do not recombine. The authors discovered the existence of 'sublimons', rearranged mitochondrial genomes present at very low levels in healthy human patients. Crucially, the different rearranged mitochondrial genomes can theoretically be interconverted through intramitochondrial recombination. The putative operation of intramitochondrial recombination should impact on our ideas of how mitochondrial genes evolve, particularly with respect to how mitochondrial genomes rearrange.

引用

收藏

页码：269 / 271

页数：3

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