Some repair-deficient mutants of Dictyostelium discoideum display enhanced susceptibilities to bleomycin

被引：8

作者：

Deering, RA

Guyer, RB

Stevens, L

WatsonThais, TE

机构：

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1996年 / 40卷 / 02期

关键词：

D O I：

10.1128/AAC.40.2.464

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Dictyostelium discoideum, a soil eukaryote, is highly resistant to DNA-damaging agents; repair mutants are more susceptible. Susceptibility to bleomycin, produced by Streptomyces verticillus, is greater for mutants which are susceptible to other agents than for resistant strains. The high potential for DNA repair may result from the need to cope with chemicals produced by other soil microorganisms.

引用

页码：464 / 467

页数：4

共 21 条

[1]

[Anonymous], 1984, The Dictyostelids

[2]

BLASQUEZ J, 1993, ANTIMICROB AGENTS CH, V37, P1982

[3] TN5-MEDIATED BLEOMYCIN RESISTANCE IN ESCHERICHIA-COLI REQUIRES THE EXPRESSION OF HOST GENES [J].