SERS - a single-molecule and nanoscale tool for bioanalytics

被引：963

作者：

Kneipp, Janina ^{[1
,2
]}

Kneipp, Harald ^{[1
]}

Kneipp, Katrin ^{[1
,3
]}

机构：

[1] Harvard Univ, Sch Med, Wellman Ctr Photomed, Boston, MA 02114 USA

[2] Fed Inst Mat Res & Testing, D-12489 Berlin, Germany

[3] Harvard Univ, MIT, Div Hlth Sci & Technol, Cambridge, MA 02139 USA

来源：

CHEMICAL SOCIETY REVIEWS | 2008年 / 37卷 / 05期

关键词：

D O I：

10.1039/b708459p

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Surface enhanced Raman scattering (SERS) at extremely high enhancement level turns the weak inelastic scattering effect of photons on vibrational quantum states into a structurally sensitive single-molecule and nanoscale probe. The effect opens up exciting opportunities for applications of vibrational spectroscopy in biology. The concept of SERS can be extended to two-photon excitation by exploiting surface enhanced hyper-Raman scattering (SEHRS). This critical review introduces the physics behind single-molecule SERS and discusses the capabilities of the effect in bioanalytics (100 references).

引用

页码：1052 / 1060

页数：9

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