Metalloporphyrin and heteropoly acid catalyzed oxidation of C=NOH bonds in an ionic liquid: biomimetic models of nitric oxide synthase

被引：73

作者：

Jain, N ^{[1
]}

Kumar, A ^{[1
]}

Chauhan, SMS ^{[1
]}

机构：

[1] Univ Delhi, Dept Chem, Delhi 110007, India

来源：

TETRAHEDRON LETTERS | 2005年 / 46卷 / 15期

关键词：

nitric oxide synthase (NOS); heteropoly acid; porphyrins; ionic liquid;

D O I：

10.1016/j.tetlet.2005.02.088

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Water soluble iron(III) porphyrins and phosphotungstic acid in an ionic liquid are effective catalysts for the H2O2 mediated oxidation of the C=NOH bond in N-hydroxyarginine and other oximes. The carbonyl compounds generated as the oxidation products can be easily isolated from the reaction media. These systems serve as biomimetic models of nitric oxide synthase (NOS) and the catalyst immobilized in an ionic liquid can be easily recycled and reused. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：2599 / 2602

页数：4

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