Biomimetic oxidation of curcumin with hydrogen peroxide catalyzed by 5,10,15,20-tetraarylporphyrinato-iron(III) chlorides in dichloromethane

被引：13

作者：

Chauhan, SMS ^{[1
]}

Kandadai, AS ^{[1
]}

Jain, N ^{[1
]}

Kumar, A ^{[1
]}

机构：

[1] Univ Delhi, Dept Chem, Delhi 110007, India

来源：

CHEMICAL & PHARMACEUTICAL BULLETIN | 2003年 / 51卷 / 11期

关键词：

biomimetic oxidation; curcumin; 5,10,15,20-tetraarylporphyrinatoiron(III) chloride; hydrogen peroxide; curcumin dimer;

D O I：

10.1248/cpb.51.1345

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The biomimetic oxidation of curcumin, a main turmeric pigment with hydrogen peroxide catalyzed by different 5,10,15,20-tetraarylporphyrinatoiron(III) chlorides [TAPFe(III)CI] in dichloromethane has been studied to give a C-C coupled curcumin dimer in 40-70% yield. The structure of the dimer has been elucidated by H-1-, C-13-NMR, IR and FAB-Mass spectroscopic data.

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页码：1345 / 1347

页数：3

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