The AprX protein of Pseudomonas aeruginosa:: a new substrate for the Apr type I secretion system

被引：50

作者：

Duong, F ^{[1
]}

Bonnet, E ^{[1
]}

Géli, V ^{[1
]}

Lazdunski, A ^{[1
]}

Murgier, M ^{[1
]}

Filloux, A ^{[1
]}

机构：

[1] CNRS, IBSM, UPR9027, Lab Ingn Syst Macromol, F-13402 Marseille 20, France

来源：

GENE | 2001年 / 262卷 / 1-2期

关键词：

protein secretion; apr gene cluster; ABC transporter; HasA;

D O I：

10.1016/S0378-1119(00)00541-2

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Protein secretion in Pseudomonas aeruginosa involves different mechanisms. The type II and type III secretory pathways control the extracellular release of a wide range of substrates. The type I secretion process, or ABC transporter, was believed to be exclusively involved in alkaline protease secretion. Recently, it was discovered that a P. aeruginosa heme binding protein, HasAp, is also secreted by a type I process. We present here the identification of a third putative type I-dependent protein of P. aeruginosa,. AprX. The function of this protein has not yet been elucidated but very interestingly it appears to be linked to the apr cluster, and organized in one single operon together with the aprD, -E and -F genes. (C) 2001 Elsevier Science B.V. All rights reserved.

引用

页码：147 / 153

页数：7

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