Probiotics reduce enterohemorrhagic Escherichia coli O157:H7-and enteropathogenic E-coli O127:H6-induced changes in polarized T84 epithelial cell monolayers by reducing bacterial adhesion and cytoskeletal rearrangements

被引：177

作者：

Sherman, PM

Johnson-Henry, KC

Yeung, HP

Ngo, PSC

Goulet, J

Tompkins, TA

机构：

[1] Univ Toronto, Hosp Sick Children, Res Inst, Toronto, ON M5G 1X8, Canada

[2] Univ Laval, Laval, PQ, Canada

[3] Inst Rosell Lallemand Inc, Montreal, PQ, Canada

来源：

INFECTION AND IMMUNITY | 2005年 / 73卷 / 08期

关键词：

D O I：

10.1128/IAI.73.8.5183-5188.2005

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The aim of this study was to determine if probiotics reduce epithelial injury following exposure to Escherichia coli O157:H7 and E. coli O127:H6. The pretreatment of intestinal (T84) cells with lactic acid-producing bacteria reduced the pathogen-induced drop in transepithelial electrical resistance. These findings demonstrate that probiotics prevent epithelial injury induced by attaching-effacing bacteria.

引用

收藏

页码：5183 / 5188

页数：6

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