Outcome of twin pregnancy in a renal transplant recipient treated with tacrolimus

被引：29

作者：

Vyas, S

Kumar, A

Piecuch, S

Hidalgo, G

Singh, A

Anderson, V

Markell, NS

Baqi, N

机构：

[1] SUNY Hlth Sci Ctr, Div Pediat Nephrol, Brooklyn, NY 11203 USA

[2] SUNY Hlth Sci Ctr, Div Pediat Nephrol & Neonatol, Dept Pathol, Brooklyn, NY 11203 USA

[3] SUNY Hlth Sci Ctr, Dept Med, Brooklyn, NY 11203 USA

来源：

TRANSPLANTATION | 1999年 / 67卷 / 03期

关键词：

D O I：

10.1097/00007890-199902150-00028

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Our report describes the outcome of a twin pregnancy in a woman who was maintained on tacrolimus after a living related renal transplant. Both babies born at 32 weeks of gestation developed severe respiratory distress requiring ventilator assistance and went on to develop congestive heart failure. Echocardiograms on both babies showed dilated heart chambers. Twin A succumbed to complications, but twin B, who was treated more aggressively with vasopressors, recovered. Autopsy findings on twin A revealed a thrombotic cardiomyopathy with degeneration of cardiac muscle. We believe that the unusual outcome in this set of twins may have been a result of cardiomyopathy secondary to tacrolimus used by the mother during her pregnancy.

引用

页码：490 / 492

页数：3

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