Current knowledge on lower virulence of Reston Ebola virus (in French: Connaissances actuelles sur la moindre virulence du virus Ebola Reston)

被引：25

作者：

Morikawa, Shigeru ^{[1
]}

Saijo, Masayuki ^{[1
]}

Kurane, Ichiro ^{[1
]}

机构：

[1] Natl Inst Infect Dis, Dept Virol 1, Tokyo 2080011, Japan

来源：

COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES | 2007年 / 30卷 / 5-6期

关键词：

Reston ebolavirus; virulence; epidemiology;

D O I：

10.1016/j.cimid.2007.05.005

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Ebola viruses (EBOV) and Marburg virus belong to the family Filoviridae, order Mononegavirales. The genus Ebolavirus consists of four species: Zaire ebolavirus (ZEBOV), Sudan ebolavirus (SEBOV), Ivory Coast ebolavirus (ICEBOV) and Reston ebolavirus (REBOV). Three species of ebolaviruses, ZEBOV, SEBOV, ICEBOV, and Marburg virus are known to be extremely pathogenic in primates and humans and cause severe hemorrhagic fever leading up to case fatality rate of some 90%, while REBOV is thought to be pathogenic in Asian monkeys but not in African monkeys and humans. Recent studies indicated several factors involved in different virulence between African EBOV and REBOV. This article reviews the history, epidemiology, and virulence of REBOV. (C) 2007 Elsevier Ltd. All rights reserved.

引用

页码：391 / 398

页数：8