Photoinduced drug release from thermosensitive AuNPs-liposome using a AuNPs-switch

被引：55

作者：

An, Xueqin ^{[1
,2
]}

Zhang, Fan ^{[2
]}

Zhu, Yinyan ^{[2
]}

Shen, Weiguo ^{[1
]}

机构：

[1] E China Univ Sci & Technol, Sch Chem & Mol Engn, Shanghai 200237, Peoples R China

[2] Nanjing Normal Univ, Jiangsu Key Lab Biofunct Mat, Coll Chem & Environm Sci, Nanjing 210097, Jiangsu, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2010年 / 46卷 / 38期

关键词：

PH-SENSITIVE LIPOSOMES; GOLD NANOPARTICLES; NANOCARRIERS; NANOCRYSTALS; FORMULATION; CHEMISTRY; DELIVERY; CARRIERS;

D O I：

10.1039/c0cc03142a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A thermosensitive liposome with embedded AuNPs in a bilayer was prepared using supercritical CO(2). The AuNPs-liposome can absorb a certain wavelength light, convert optical energy into heat, induce phase transition, and release drug. The results show that drug release from the liposome is due to the photothermic effects inducing phase transition of the liposome rather than destruction of the liposome structure.

引用

页码：7202 / 7204

页数：3

共 23 条

[1] The liposomal formulation of doxorubicin [J].

Abraham, SA ;

Waterhouse, DN ;

Mayer, LD ;

Cullis, PR ;

Madden, TD ;

Bally, MB .

LIPOSOMES, PT E, 2005, 391 :71-97

[2] Chemistry and properties of nanocrystals of different shapes [J].

Burda, C ;

Chen, XB ;

Narayanan, R ;

El-Sayed, MA .

CHEMICAL REVIEWS, 2005, 105 (04) :1025-1102

[3] Gold nanoparticles: Assembly, supramolecular chemistry, quantum-size-related properties, and applications toward biology, catalysis, and nanotechnology [J].

Daniel, MC ;

Astruc, D .

CHEMICAL REVIEWS, 2004, 104 (01) :293-346

[4] Applications of liposomes in ophthalmology [J].

Ebrahim, S ;

Peyman, GA ;

Lee, PJ .

SURVEY OF OPHTHALMOLOGY, 2005, 50 (02) :167-182

[5] Pros and cons of the liposome platform in cancer drug targeting [J].

Gabizon, Alberto A. ;

Shmeeda, Hilary ;

Zalipsky, Samuel .

JOURNAL OF LIPOSOME RESEARCH, 2006, 16 (03) :175-183

[6] Acoustically active liposomes for drug encapsulation and ultrasound-triggered release [J].

Huang, SL ;

MacDonald, RC .

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 2004, 1665 (1-2) :134-141

[7] Smart drug carriers: PEGylated TATp-Modified pH-Sensitive Liposomes [J].

Kale, Amit A. ;

Torchilin, Vladimir P. .

JOURNAL OF LIPOSOME RESEARCH, 2007, 17 (3-4) :197-203

[8] pH-sensitive liposomes - principle and application in cancer therapy [J].

Karanth, H. ;

Murthy, R. S. R. .

JOURNAL OF PHARMACY AND PHARMACOLOGY, 2007, 59 (04) :469-483

[9] Shape and size dependence of radiative, non-radiative and photothermal properties of gold nanocrystals [J].

Link, S ;

El-Sayed, MA .

INTERNATIONAL REVIEWS IN PHYSICAL CHEMISTRY, 2000, 19 (03) :409-453

[10] Visible-light-stimulated destabilization of PEG-liposomes [J].

Mueller, A ;

Bondurant, B ;

O'Brien, DF .

MACROMOLECULES, 2000, 33 (13) :4799-4804

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