Modulating the immune response with dendritic cells and their growth factors

被引:232
作者
Pulendran, B
Maraskovsky, E
Banchereau, J
Maliszewski, C
机构
[1] Baylor Inst Immunol, Dallas, TX 75204 USA
[2] Immunex Res & Dev Corp, Seattle, WA 98101 USA
关键词
D O I
10.1016/S1471-4906(00)01794-4
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Different subsets of dendritic cells (DCs) appear to play a role in determining the specific cytokines secreted by T helper (Th) cells. A model is proposed that links together factors such as the pathogen, microenvironment. DCs andT cells in a mechanism that results in a flexible determination of T-cell polarization.
引用
收藏
页码:41 / 47
页数:7
相关论文
共 70 条
[1]   Definition of dendritic cell subpopulations present in the spleen, Peyer's patches, lymph nodes, and skin of the mouse [J].
Anjuère, F ;
Martín, P ;
Ferrero, I ;
Fraga, ML ;
del Hoyo, GM ;
Wright, N ;
Ardavin, C .
BLOOD, 1999, 93 (02) :590-598
[2]   THYMIC DENDRITIC CELLS AND T-CELLS DEVELOP SIMULTANEOUSLY IN THE THYMUS FROM A COMMON PRECURSOR POPULATION [J].
ARDAVIN, C ;
WU, L ;
LI, CL ;
SHORTMAN, K .
NATURE, 1993, 362 (6422) :761-763
[3]   Granulocyte-colony stimulating factor mobilizes T helper 2-inducing dendritic cells [J].
Arpinati, M ;
Green, CL ;
Heimfeld, S ;
Heuser, JE ;
Anasetti, C .
BLOOD, 2000, 95 (08) :2484-2490
[4]   Immunobiology of dendritic cells [J].
Banchereau, J ;
Briere, F ;
Caux, C ;
Davoust, J ;
Lebecque, S ;
Liu, YT ;
Pulendran, B ;
Palucka, K .
ANNUAL REVIEW OF IMMUNOLOGY, 2000, 18 :767-+
[5]   Dendritic cells and the control of immunity [J].
Banchereau, J ;
Steinman, RM .
NATURE, 1998, 392 (6673) :245-252
[6]   Identification of a committed T cell precursor population in adult human peripheral blood [J].
Bruno, L ;
Res, P ;
Dessing, M ;
Cella, M ;
Spits, H .
JOURNAL OF EXPERIMENTAL MEDICINE, 1997, 185 (05) :875-884
[7]   CD34(+) hematopoietic progenitors from human cord blood differentiate along two independent dendritic cell pathways in response to GM-CSF+TNF alpha [J].
Caux, C ;
Vanbervliet, B ;
Massacrier, C ;
DezutterDambuyant, C ;
deSaintVis, B ;
Jacquet, C ;
Yoneda, K ;
Imamura, S ;
Schmitt, D ;
Banchereau, J .
JOURNAL OF EXPERIMENTAL MEDICINE, 1996, 184 (02) :695-706
[8]   GM-CSF AND TNF-ALPHA COOPERATE IN THE GENERATION OF DENDRITIC LANGERHANS CELLS [J].
CAUX, C ;
DEZUTTERDAMBUYANT, C ;
SCHMITT, D ;
BANCHEREAU, J .
NATURE, 1992, 360 (6401) :258-261
[9]   Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type I interferon [J].
Cella, M ;
Jarrossay, D ;
Facchetti, F ;
Alebardi, O ;
Nakajima, H ;
Lanzavecchia, A ;
Colonna, M .
NATURE MEDICINE, 1999, 5 (08) :919-923
[10]   Dendritic cells discriminate between yeasts and hyphae of the fungus Candida albicans:: Implications for initiation of T helper cell immunity in vitro and in vivo [J].
d'Ostiani, CF ;
Del Sero, G ;
Bacci, A ;
Montagnoli, C ;
Spreca, A ;
Mencacci, A ;
Ricciardi-Castagnoli, P ;
Romani, L .
JOURNAL OF EXPERIMENTAL MEDICINE, 2000, 191 (10) :1661-1673