Regulation of hypaxial muscle development

被引：65

作者：

Dietrich, S ^{[1
]}

机构：

[1] Kings Coll London, Guys Hosp, Dept Craniofacial Dev, London SE1 9RT, England

来源：

CELL AND TISSUE RESEARCH | 1999年 / 296卷 / 01期

关键词：

somite patterning; hypaxial muscles; cell migration; Pax3; cMet; Lbxl;

D O I：

10.1007/s004410051278

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The majority of skeletal muscles in higher vertebrates are hypaxial and stem from the lateral lip of the dermomyotomes. Various external signals converge on the dorsolateral quadrant of the somite to specify the hypaxial muscle precursors, to discriminate between migratory and non-migratory cells and to allow delamination of precursors destined for long-range migration. Within the somite, Pax3 acts as upstream regulator of hypaxial muscle development. Downstream targets are cMet and Lbx1, which may independently control identity, differentiation and motility of migratory muscle precursors.

引用

页码：175 / 182

页数：8

共 60 条

[31] MIGRATION OF MYOGENIC CELLS FROM THE SOMITES INTO THE LEG REGION OF AVIAN EMBRYOS - ULTRASTRUCTURAL-STUDY [J].

JACOB, M ;

CHRIST, B ;

JACOB, HJ .

ANATOMY AND EMBRYOLOGY, 1979, 157 (03) :291-309

[32] MOUSE LBX1 AND HUMAN LBX1 DEFINE A NOVEL MAMMALIAN HOMEOBOX GENE FAMILY RELATED TO THE DROSOPHILA LADY BIRD GENES [J].

JAGLA, K ;

DOLLE, P ;

MATTEI, MG ;

JAGLA, T ;

SCHUHBAUR, B ;

DRETZEN, G ;

BELLARD, F ;

BELLARD, M .

MECHANISMS OF DEVELOPMENT, 1995, 53 (03) :345-356

[33]

Kablar B, 1997, DEVELOPMENT, V124, P4729

[34] Uncoupling of Grb2 from the Met receptor in vivo reveals complex roles in muscle development [J].

Maina, F ;

Casagranda, F ;

Audero, E ;

Simeone, A ;

Comoglio, PM ;

Klein, R ;

Ponzetto, C .

CELL, 1996, 87 (03) :531-542

[35]

Marcelle C, 1997, DEVELOPMENT, V124, P3955

[36] Ectopic Pax-3 activates MyoD and Myf-5 expression in embryonic mesoderm and neural tissue [J].

Maroto, M ;

Reshef, R ;

Munsterberg, AE ;

Koester, S ;

Goulding, M ;

Lassar, AB .

CELL, 1997, 89 (01) :139-148

[37] Noggin-mediated antagonism of BMP signaling is required for growth and patterning of the neural tube and somite [J].

McMahon, JA ;

Takada, S ;

Zimmerman, LB ;

Fan, CM ;

Harland, RM ;

McMahon, AP .

GENES & DEVELOPMENT, 1998, 12 (10) :1438-1452

[38] Pax-3 is necessary but not sufficient for lbx1 expression in myogenic precursor cells of the limb [J].

Mennerich, D ;

Schäfer, K ;

Braun, T .

MECHANISMS OF DEVELOPMENT, 1998, 73 (02) :147-158

[39]

MUNSTERBERG AE, 1995, DEVELOPMENT, V121, P651

[40] COMBINATORIAL SIGNALING BY SONIC HEDGEHOG AND WNT FAMILY MEMBERS INDUCES MYOGENIC BHLH GENE-EXPRESSION IN THE SOMITE [J].

MUNSTERBERG, AE ;

KITAJEWSKI, J ;

BUMCROT, DA ;

MCMAHON, AP ;

LASSAR, AB .

GENES & DEVELOPMENT, 1995, 9 (23) :2911-2922

← 1 2 3 4 5 6 →