First anti-oestrogen in the cyclopentadienyl rhenium tricarbonyl series.: Synthesis and study of antiproliferative effects

被引：65

作者：

Jaouen, G

Top, S

Vessières, A

Pigeon, P

Leclercq, G

Laios, I

机构：

[1] Ecole Natl Super Chim Paris, Lab Chim Organomet, UMR 7576, F-75231 Paris 05, France

[2] Inst Jules Bordet, Lab Cancerol Mammaire, B-1000 Brussels, Belgium

来源：

CHEMICAL COMMUNICATIONS | 2001年 / 04期

关键词：

D O I：

10.1039/b009553m

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A route to the organometallic complex 8 is described, along with a study of its antiproliferative effects on breast cancer cell lines; in the examples studied, 8 behaves in a very similar manner to tamoxifen, suggesting new possibilities for applications in organometallic chemistry.

引用

收藏

页码：383 / 384

页数：2

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