Protein separations using membrane filtration: New opportunities for whey fractionation

被引：159

作者：

Zydney, AL ^{[1
]}

机构：

[1] Univ Delaware, Dept Chem Engn, Newark, DE 19716 USA

来源：

INTERNATIONAL DAIRY JOURNAL | 1998年 / 8卷 / 03期

关键词：

membrane; ultrafiltration; proteins; whey fractionation;

D O I：

10.1016/S0958-6946(98)00045-4

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

There is considerable commercial interest in the preparation of individual whey proteins for food, nutraceutical, and therapeutic applications. Recent developments in membrane filtration have provided exciting new opportunities for large-scale protein fractionation. This manuscript provides an overview of the previous work on protein separations using membrane filtration, including the importance of solution pH and ionic strength to obtain very high resolution separations. Specific data are shown for the separation of hemoglobin from BSA and for the purification of immunoglobulins from a complex feed stream using a gradient diafiltration process. The potential applications of membrane systems for whey protein fractionation are also examined. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：243 / 250

页数：8

共 42 条

[1] PRODUCTION OF ENRICHED PROTEIN-FRACTIONS OF BETA-LACTOGLOBULIN AND ALPHA-LACTALBUMIN FROM CHEESE WHEY [J].