Titanium catalysed enantioselective addition of allyltributyltin to aldehydes: a simple and easily reproducible procedure

被引：38

作者：

Doucet, H ^{[1
]}

Santelli, M ^{[1
]}

机构：

[1] CNRS, Fac Sci St Jerome, Synth Organ Lab, F-13397 Marseille 20, France

来源：

TETRAHEDRON-ASYMMETRY | 2000年 / 11卷 / 20期

关键词：

D O I：

10.1016/S0957-4166(00)00374-8

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

We describe here an extremely simple procedure for the enantioselective addition of allyltributyltin to aldehydes in the presence of a binaphthol-titanium complex. In toluene or pentane, the reaction can be performed at room temperature in the absence of molecular sieves without a decrease in the enantioselectivity. Enantiomeric excesses of up to 99% can be obtained in the most favourable cases. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：4163 / 4169

页数：7

共 23 条

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