Stem Cells and Osteoporosis Therapy

被引:86
作者
Teitelbaum, Steven L. [1 ]
机构
[1] Washington Univ, Sch Med, Dept Pathol & Immunol, St Louis, MO 63110 USA
关键词
PARATHYROID-HORMONE; ALENDRONATE;
D O I
10.1016/j.stem.2010.10.004
中图分类号
Q813 [细胞工程];
学科分类号
100113 [医学细胞生物学];
摘要
Skeletal remodeling requires recruitment of osteoblast precursors, in the form of MSCs, to the bone surface. In this issue of Cell Stem Cell, Wu et al. (2010) demonstrate that this event is mediated by osteoclastic mobilization of active transforming growth factor beta 1, which is inhibited by a common antiosteoporosis drug.
引用
收藏
页码:553 / 554
页数:2
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