Mammalian sperm chromatin structure and assessment of DNA fragmentation

被引:47
作者
Andrabi, S. M. H. [1 ]
机构
[1] Natl Agr Res Ctr, Inst Anim Sci, Anim Reprod Lab, Islamabad 45500, Pakistan
关键词
sperm chromatin; DNA fragmentation; mammals; TERMINAL DEOXYNUCLEOTIDYL TRANSFERASE; DEOXYRIBONUCLEIC-ACID FRAGMENTATION; BASIC NUCLEAR PROTEINS; HUMAN SPERMATOZOA; STRAND BREAKS; IN-VITRO; FERTILIZING ABILITY; OXIDATIVE STRESS; MALE-INFERTILITY; DAMAGE;
D O I
10.1007/s10815-007-9177-y
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
This review article illustrates the biology of mammalian sperm chromatin structure. The possible causes of DNA (deoxyribonucleic acid) fragmentation are discussed. Also available molecular techniques for assessment of mammalian sperm DNA damage are described.
引用
收藏
页码:561 / 569
页数:9
相关论文
共 130 条
[1]   Role of sperm chromatin abnormalities and DNA damage in male infertility [J].
Agarwal, A ;
Said, TM .
HUMAN REPRODUCTION UPDATE, 2003, 9 (04) :331-345
[2]  
Agarwal A., 2004, Textbook of Assisted Reproductive Techniques, P93
[3]  
Ahmadi A, 1999, J EXP ZOOL, V284, P696, DOI 10.1002/(SICI)1097-010X(19991101)284:6<696::AID-JEZ11>3.0.CO
[4]  
2-E
[5]  
Aitken RJ, 1997, MOL REPROD DEV, V47, P468, DOI 10.1002/(SICI)1098-2795(199708)47:4<468::AID-MRD14>3.0.CO
[6]  
2-S
[7]   Multiple forms of redox activity in populations of human spermatozoa [J].
Aitken, RJ ;
Ryan, AL ;
Curry, BJ ;
Baker, MA .
MOLECULAR HUMAN REPRODUCTION, 2003, 9 (11) :645-661
[8]   Relative impact of oxidative stress on the functional competence and genomic integrity of human spermatozoa [J].
Aitken, RJ ;
Gordon, E ;
Harkiss, D ;
Twigg, JP ;
Milne, P ;
Jennings, Z ;
Irvine, DS .
BIOLOGY OF REPRODUCTION, 1998, 59 (05) :1037-1046
[9]  
Akama K, 1996, J BIOCHEM-TOKYO, V119, P448
[10]  
Anderson D, 1997, TERATOGEN CARCIN MUT, V17, P45, DOI 10.1002/(SICI)1520-6866(1997)17:2<45::AID-TCM1>3.3.CO