Perspectives in paramagnetic NMR of metalloproteins

被引：86

作者：

Bertini, Ivano ^{[1
,2
]}

Luchinat, Claudio ^{[1
,3
]}

Parigi, Giacomo ^{[1
,3
]}

Pierattelli, Roberta ^{[1
,2
]}

机构：

[1] Univ Florence, Magnet Resonance Ctr, I-50019 Sesto Fiorentino, FI, Italy

[2] Univ Florence, Dept Chem, I-50121 Florence, Italy

[3] Univ Florence, Dept Agr Biotechnol, I-50121 Florence, Italy

来源：

DALTON TRANSACTIONS | 2008年 / 29卷 / 29期

关键词：

D O I：

10.1039/b719526e

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

NMR experiments and tools for the characterization of the structure and dynamics of paramagnetic proteins are presented here. The focus is on the importance of C-13 direct-detection NMR for the assignment of paramagnetic systems in solution, on the information contained in paramagnetic effects observed both in solution and in the solid state, and on novel paramagnetism-based tools for the investigation of conformational heterogeneity in protein-protein complexes or in multi-domain proteins.

引用

收藏

页码：3782 / 3790

页数：9

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