Transcription-associated protein families are primarily taxon-specific

被引：23

作者：

Coulson, RMR ^{[1
]}

Enright, AJ ^{[1
]}

Ouzounis, CA ^{[1
]}

机构：

[1] European Bioinformat Inst, EMBL Cambridge Outstn, Res Programme, Computat Genom Grp, Cambridge CB10 1SD, England

来源：

BIOINFORMATICS | 2001年 / 17卷 / 01期

关键词：

D O I：

10.1093/bioinformatics/17.1.95

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The mechanisms controlling gene regulation appear to be fundamentally different in eukaryotes and prokaryotes (Struhl (1999) Cell, 98, 1-4). To investigate this diversity further, we have analysed the distribution of all known transcription-associated proteins (TAPs), as reflected by sequence database annotations. Our results for the primary phylogenetic domains (Archaea, Bacteria and Eukaryota) show that TAP families are mostly taxon-specific and very few transcriptional regulators are common across these domains.

引用

页码：95 / 97

页数：3

共 10 条

[1] Transcriptional regulation of an archaeal operon in vivo and in vitro
Bell, SD
Cairns, SS
Robson, RL
Jackson, SP
[J]. MOLECULAR CELL, 1999, 4 (06) : 971 - 982
[2] GeneRAGE: a robust algorithm for sequence clustering and domain detection
Enright, AJ
Ouzounis, CA
[J]. BIOINFORMATICS, 2000, 16 (05) : 451 - 457
[3] Protein interaction maps for complete genomes based on gene fusion events
Enright, AJ
Iliopoulos, I
Kyrpides, NC
Ouzounis, CA
[J]. NATURE, 1999, 402 (6757) : 86 - 90
[4] ORIGIN AND EVOLUTION OF ORGANELLE GENOMES
GRAY, MW
[J]. CURRENT OPINION IN GENETICS & DEVELOPMENT, 1993, 3 (06) : 884 - 890
[5] Transcription in Archaea
Kyrpides, NC
Ouzounis, CA
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (15) : 8545 - 8550
[6] How can we use our growing understanding of gene transcription to discover effective new medicines?
Latchman, DS
[J]. CURRENT OPINION IN BIOTECHNOLOGY, 1997, 8 (06) : 713 - 717
[7] ISOLATION OF CDNA-ENCODING A BINDING-PROTEIN SPECIFIC TO 5'-PHOSPHORYLATED SINGLE-STRANDED-DNA WITH G-RICH SEQUENCES
MIZUTA, TR
FUKITA, Y
MIYOSHI, T
SHIMIZU, A
HONJO, T
[J]. NUCLEIC ACIDS RESEARCH, 1993, 21 (08) : 1761 - 1766
[8] Arabidopsis transcription factors:: Genome-wide comparative analysis among eukaryotes
Riechmann, JL
Heard, J
Martin, G
Reuber, L
Jiang, CZ
Keddie, J
Adam, L
Pineda, O
Ratcliffe, OJ
Samaha, RR
Creelman, R
Pilgrim, M
Broun, P
Zhang, JZ
Ghandehari, D
Sherman, BK
Yu, CL
[J]. SCIENCE, 2000, 290 (5499) : 2105 - 2110
[9] Fundamentally different logic of gene regulation in eukaryotes and prokaryotes
Struhl, K
[J]. CELL, 1999, 98 (01) : 1 - 4
[10] Ser727-dependent recruitment of MCM5 by Stat1α in IFN-γ-induced transcriptional activation
Zhang, JJ
Zhao, YM
Chait, BT
Lathem, WW
Ritzi, M
Knippers, R
Darnell, JE
[J]. EMBO JOURNAL, 1998, 17 (23) : 6963 - 6971

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