Lateral gene transfer in Salmonella

被引:94
作者
Porwollik, S [1 ]
McClelland, M [1 ]
机构
[1] Sidney Kimmel Canc Ctr, San Diego, CA 92121 USA
关键词
lateral gene transfer; microarray; comparative genomics; Salmonella;
D O I
10.1016/S1286-4579(03)00186-2
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Comparative genomics and microarrays reveal that the genomes of different Salmonella enterica serovars are distinguished from each other by the presence or absence of hundreds of genes. The distribution of these variable genome regions is often not clonal. Therefore, lateral gene transfer (LGT) plays an important role in diversity among Salmonella. Overall, almost one quarter of the entire S. enterica sv Typhimurium genome may have been introduced by LGT. (C) 2003 Editions scientifiques et medicales Elsevier SAS. All rights reserved.
引用
收藏
页码:977 / 989
页数:13
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