Usefulness of shear stress pattern in predicting neointima distribution in sirolimus-eluting stents in coronary arteries

被引:76
作者
Gijsen, FJH [1 ]
Oortman, RM [1 ]
Wentzel, JJ [1 ]
Schuurbiers, JCH [1 ]
Tanabe, K [1 ]
Degertekin, M [1 ]
Ligthart, JM [1 ]
Thury, A [1 ]
de Feyter, PJ [1 ]
Serruys, PW [1 ]
Slager, CJ [1 ]
机构
[1] Erasmus MC Rotterdam, Thoraxctr, Dept Cardiol, NL-3000 DR Rotterdam, Netherlands
关键词
D O I
10.1016/j.amjcard.2003.08.017
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The true 3-dimensional neointimal thickness distribution in sirolimus-eluting stents was investigated in relation to the shear stress distribution, which was obtained from computational fluid dynamics calculations. Small pits were observed between the stent struts in all patients, and a significant inverse relation between neointimal thickness and shear stress was found, indicating that deeper pits were present in the outside curve of the stented segments. (C) 2003 by Excerpta Medica, Inc.
引用
收藏
页码:1325 / 1328
页数:4
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