A supramolecular-hydrogel-encapsulated hemin as an artificial enzyme to mimic peroxidase

被引：366

作者：

Wang, Qigang

Yang, Zhimou

Zhang, Xieqiu

Xiao, Xudong

Chang, Chi K. ^{[1
]}

Xu, Bing

机构：

[1] Hong Kong Univ Sci & Technol, Dept Chem, Hong Kong, Hong Kong, Peoples R China

[2] Hong Kong Univ Sci & Technol, Dept Phys, Hong Kong, Hong Kong, Peoples R China

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2007年 / 46卷 / 23期

关键词：

biotransformations; enzyme mimetics; hemin; heterogeneous catalysis; hydrogels;

D O I：

10.1002/anie.200700404

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Figure Presented) Faking it: The use of a supramolecular hydrogel as the structural component of artificial enzymes provides a new and useful approach to the development of biomimetic catalysts. In toluene, hemin chloride encapsulated in such a hydrogel achieves about 60% nascent catalytic activity of horseradish peroxidase. Additionally, the activity of hemin in the hydrogel is 387.1 times greater than that of free hemin. © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.

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页码：4285 / 4289

页数：5

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