Morphological changes of Rhizopus chinesis 12 in submerged culture and its relationship with antibiotic production

被引：34

作者：

Du, LX ^{[1
]}

Jia, SJ

Lu, FP

机构：

[1] Tianjin Inst Light Ind, Dept Food Engn, Appl Microbiol Lab, Tianjin 300222, Peoples R China

[2] Shanghai Inst Pharmaceut Ind, Shanghai 200040, Peoples R China

来源：

PROCESS BIOCHEMISTRY | 2003年 / 38卷 / 12期

关键词：

Rhizopus chinesis 12; morphology; antibiotic production; pellets;

D O I：

10.1016/S0032-9592(02)00089-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

The effects of nitrogen source, the concentration of spore suspension and dissolved oxygen tension on morphology and antibiotic production of RhizPous chinesis 12 were investigated. The nitrogen source greatly affected fungal morphology and antibiotic production. In the medium containing corn steep liquor, pellets were formed and highest antibiotic production (6328.0 U ml(-1)) was achieved. With a concentration of spore suspension of 10(7) spores per ml, the highest antibiotic production was obtained and pellets were formed. In addition, improvement of dissolved oxygen tension was favourable for antibiotic production and pellets formation. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：1643 / 1646

页数：4

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