Cellular binding of nanoparticles in the presence of serum proteins

被引：55

作者：

Doorley, Gerard W.

Payne, Christine K. ^{[1
]}

机构：

[1] Georgia Inst Technol, Sch Chem & Biochem, Atlanta, GA 30332 USA

来源：

CHEMICAL COMMUNICATIONS | 2011年 / 47卷 / 01期

关键词：

CONFORMATIONALLY MODIFIED ALBUMINS; NONVIRAL GENE DELIVERY; IN-VIVO; SURFACE PROTEOGLYCANS; HEPARAN-SULFATE; QUANTUM DOTS; CELLS; PEPTIDE; ENDOCYTOSIS; TRANSDUCTION;

D O I：

10.1039/c0cc02618b

中图分类号：

O6 [化学];

学科分类号：

070301 [无机化学];

摘要：

Cellular binding of cationic nanoparticles in the presence of serum proteins was probed with two-colour fluorescence micro-scopy. Cationic nanoparticles associate with serum proteins in solution and bind to the cell surface as a single anionic complex. Displacement of serum proteins from the nanoparticles was found to be protein dependent.

引用

收藏

页码：466 / 468

页数：3

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