Empirical relationships between the sea surface partial pressure of carbon dioxide (pCO(2)), sea surface chlorophyll-a concentration (Chl-a), and sea surface temperature (SST), were derived from shipboard pCO(2) measurements in sea water and atmosphere, in-situ Chl-a, and SST data along cruise tracks between Zhongshan Station in East Antarctica and Changcheng Station on the Antarctic Peninsula in December 1999, January 2000, December 2004 and January 2005 during the CHINARE XVI and XXI campaigns. These relationships were then applied to datasets of remotely sensed Chl-a and SST to estimate the monthly air-sea carbon flux and the uptake of atmospheric CO2 in the southern Atlantic and Indian Ocean. The results show significant spatial and temporal variability of carbon flux in the southern Atlantic and Indian Ocean. The monthly uptakes of atmospheric CO2 in the region from 50 degrees S to the ice edge between 60 degrees W and 80 degrees E are -0.00355 GtC, -0.00573 GtC in December 1999 and January 2000, and -0.00361 GtC, -0.00525 GtC in December 2004 and January 2005, respectively. (C) 2011 Elsevier Inc. All rights reserved.