Postoperative nausea and vomiting. Propofol or thiopentone: Does choice of induction agent affect outcome?

被引：18

作者：

Myles, PS ^{[1
]}

Hendrata, M ^{[1
]}

Bennett, AM ^{[1
]}

Langley, M ^{[1
]}

Buckland, MR ^{[1
]}

机构：

[1] ALFRED HOSP,DEPT ANAESTHESIA & PAIN MANAGEMENT,MELBOURNE,VIC,AUSTRALIA

来源：

ANAESTHESIA AND INTENSIVE CARE | 1996年 / 24卷 / 03期

关键词：

anaesthetics; intravenous; propofol; complications; postoperative nausea; vomiting;

D O I：

10.1177/0310057X9602400309

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

Postoperative nausea and vomiting (PONV) has many causes, including anaesthetic drugs. Choice of induction agent may affect the incidence of PONV, though the evidence is conflicting. We have analysed our database of outcome after surgery. Data on 4173 patients were analysed using multivariate logistic regression, with an overall incidence of PONV 21.3%. Propofol, when compared to thiopentone for induction of anaesthesia, resulted in an 18% reduction in PONV (OR=0.82, P=0.03), The likely postoperative benefits of propofol may outweigh concerns about its additional cost.

引用

页码：355 / 359

页数：5

共 18 条

[1] INDUCTION AND RECOVERY CHARACTERISTICS OF PROPOFOL, THIOPENTAL AND ETOMIDATE [J].

BOYSEN, K ;

SANCHEZ, R ;

KRINTEL, JJ ;

HANSEN, M ;

HAAR, PM ;

DYRBERG, V .

ACTA ANAESTHESIOLOGICA SCANDINAVICA, 1989, 33 (08) :689-692

[2]

COHEN MM, 1994, ANESTH ANALG, V78, P7

[3] YOU CANNOT EXCLUDE THE EXPLANATION YOU HAVE NOT CONSIDERED [J].

DATTA, M .

LANCET, 1993, 342 (8867) :345-347

[4] PROPOFOL NITROUS OXIDE VERSUS THIOPENTAL-ISOFLURANE NITROUS OXIDE FOR GENERAL-ANESTHESIA [J].

DOZE, VA ;

SHAFER, A ;

WHITE, PF .

ANESTHESIOLOGY, 1988, 69 (01) :63-71

[5] A COMPARISON OF PROPOFOL AND THIOPENTONE AS INDUCTION-AGENTS IN OUTPATIENT SURGERY [J].

EDELIST, G .

CANADIAN JOURNAL OF ANAESTHESIA-JOURNAL CANADIEN D ANESTHESIE, 1987, 34 (02) :110-116

[6] NAUSEA - THE MOST IMPORTANT FACTOR DETERMINING LENGTH OF STAY AFTER AMBULATORY ANESTHESIA - A COMPARATIVE-STUDY OF ISOFLURANE AND OR PROPOFOL TECHNIQUES [J].

GREEN, G ;

JONSSON, L .

ACTA ANAESTHESIOLOGICA SCANDINAVICA, 1993, 37 (08) :742-746

[7] WHICH INTRAVENOUS INDUCTION AGENT FOR DAY SURGERY - A COMPARISON OF PROPOFOL, THIOPENTONE, METHOHEXITONE AND ETOMIDATE [J].

HEATH, PJ ;

KENNEDY, DJ ;

OGG, TW ;

DUNLING, C ;

GILKS, WR .

ANAESTHESIA, 1988, 43 (05) :365-368

[8]

JOBALIA N, 1994, ANESTHESIOLOGY, V81, pA33

[9] THE STUDY OF POSTOPERATIVE NAUSEA AND VOMITING [J].

KORTTILA, K .

BRITISH JOURNAL OF ANAESTHESIA, 1992, 69 (07) :S20-S23

[10] RANDOMIZED COMPARISON OF RECOVERY AFTER PROPOFOL-NITROUS OXIDE VERSUS THIOPENTONE-ISOFLURANE-NITROUS OXIDE ANESTHESIA IN PATIENTS UNDERGOING AMBULATORY SURGERY [J].

KORTTILA, K ;

OSTMAN, P ;

FAURE, E ;

APFELBAUM, JL ;

PRUNSKIS, J ;

EKDAWI, M ;

ROIZEN, MF .

ACTA ANAESTHESIOLOGICA SCANDINAVICA, 1990, 34 (05) :400-403

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