Planar-chiral cyclopalladated ferrocenyl amines and imines as enantioselective catalysts for allylic imidate rearrangements

被引：56

作者：

Cohen, F ^{[1
]}

Overman, LE ^{[1
]}

机构：

[1] Univ Calif Irvine, Dept Chem, Irvine, CA 92697 USA

来源：

TETRAHEDRON-ASYMMETRY | 1998年 / 9卷 / 18期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1016/S0957-4166(98)00341-3

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A series of enantiopure cyclopalladated ferrocenyl amines and imines were synthesized and evaluated as catalysts for the [3,3]-rearrangement of allylic benzimidates to allylic benzamides. Yields and extent of enantioselection were found to be highly dependent upon the counter-ion, with a high of 78% yield and 73% ee being realized under optimum conditions. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：3213 / 3222

页数：10

共 21 条

[1] REDUCTIVE ALKYLATIONS OF DIMETHYLAMINE USING TITANIUM(IV) ISOPROPOXIDE AND SODIUM-BOROHYDRIDE - AN EFFICIENT, SAFE, AND CONVENIENT METHOD FOR THE SYNTHESIS OF N,N-DIMETHYLATED TERTIARY-AMINES [J].