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Histone deacetylase inhibitors: Development of suberoylanilide hydroxamic acid (SAHA) for the treatment of cancers

被引：82
作者：
Richon, VM
Zhou, XB
Rifkind, RA
Marks, PA
机构：
[1] Mem Sloan Kettering Canc Ctr, Cell Biol Program, New York, NY 10021 USA
[2] Cornell Univ, Grad Sch Med Sci, New York, NY 10021 USA
来源：
BLOOD CELLS MOLECULES AND DISEASES | 2001年 / 27卷 / 01期
关键词：
D O I：
10.1006/bcmd.2000.0376
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
[No abstract available]
引用
收藏
页码：260 / 264
页数：5
相关论文
共 58 条
  • [31] Histone deacetylase inhibitors: Inducers of differentiation or apoptosis of transformed cells
    Marks, PA
    Richon, VM
    Rifkind, RA
    [J]. JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2000, 92 (15): : 1210 - 1216
  • [32] HDAC4 deacetylase associates with and represses the MEF2 transcription factor
    Miska, EA
    Karlsson, C
    Langley, E
    Nielsen, SJ
    Pines, J
    Kouzarides, T
    [J]. EMBO JOURNAL, 1999, 18 (18) : 5099 - 5107
  • [33] Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
    Nan, XS
    Ng, HH
    Johnson, CA
    Laherty, CD
    Turner, BM
    Eisenman, RN
    Bird, A
    [J]. NATURE, 1998, 393 (6683) : 386 - 389
  • [34] Poluha W, 1996, MOL CELL BIOL, V16, P1335
  • [35] Histone deacetylase inhibitor selectively induces p21WAF1 expression and gene-associated histone acetylation
    Richon, VM
    Sandhoff, TW
    Rifkind, RA
    Marks, PA
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (18) : 10014 - 10019
  • [36] Second generation hybrid polar compounds are potent inducers of transformed cell differentiation
    Richon, VM
    Webb, Y
    Merger, R
    Sheppard, T
    Jursic, B
    Ngo, L
    Civoli, F
    Breslow, R
    Rifkind, RA
    Marks, PA
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (12) : 5705 - 5708
  • [37] A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases
    Richon, VM
    Emiliani, S
    Verdin, E
    Webb, Y
    Breslow, R
    Rifkind, RA
    Marks, PA
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (06) : 3003 - 3007
  • [38] A synthetic inhibitor of histone deacetylase, MS-27-275, with marked in vivo antitumor activity against human tumors
    Saito, A
    Yamashita, T
    Mariko, Y
    Nosaka, Y
    Tsuchiya, K
    Ando, T
    Suzuki, T
    Tsuruo, T
    Nakanishi, O
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (08) : 4592 - 4597
  • [39] Histone deacetylase inhibition selectively alters the activity and expression of cell cycle proteins leading to specific chromatin acetylation and antiproliferative effects
    Sambucetti, LC
    Fischer, DD
    Zabludoff, S
    Kwon, PO
    Chamberlin, H
    Trogani, N
    Xu, H
    Cohen, D
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (49) : 34940 - 34947
  • [40] Histone deacetylase inhibitor activates the WAF1/Cip1 gene promoter through the Sp1 sites
    Sowa, Y
    Orita, T
    Minamikawa, S
    Nakano, K
    Mizuno, T
    Nomura, H
    Sakai, T
    [J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1997, 241 (01) : 142 - 150
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