An over four millennium story behind qinghaosu (Artemisinin) - A fantastic antimalarial drug from a traditional Chinese herb

被引：141

作者：

Li, Y

Wu, YL

机构：

[1] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Bioorgan & Nat Prod Chem, Shanghai 200032, Peoples R China

[2] Chinese Acad Sci, Shanghai Inst Biol Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China

来源：

CURRENT MEDICINAL CHEMISTRY | 2003年 / 10卷 / 21期

关键词：

artemisinin; chemistry; structure determination; synthesis; pharmacology; antimalarial; mechanism of action; prevention for schistosoma; antitumor; immunoregulation;

D O I：

10.2174/0929867033456710

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

This article reviews the discovery and the further studies on qinghaosu and its derivatives or analogs over the last decades in the fields of medicinal chemistry and some pharmacology research, with an emphasis on the progress achieved in China.

引用

页码：2197 / 2230

页数：34

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