Zeolite catalyzed selective deprotection of di- and tri-O-isopropylidene sugar acetals

被引：15

作者：

Bhaskar, Pallooru Muni ^{[1
]}

Mathiselvam, Manoharan ^{[1
]}

Loganathan, Duraikkannu ^{[1
]}

机构：

[1] Indian Inst Technol, Dept Chem, Madras 600036, Tamil Nadu, India

来源：

CARBOHYDRATE RESEARCH | 2008年 / 343卷 / 10-11期

关键词：

O-isopropylidene acetals; carbohydrates; hydrolysis; zeolites and solid acids;

D O I：

10.1016/j.carres.2008.05.006

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

H-Beta zeolite, a microporous solid acid, is demonstrated to be an efficient catalyst for the selective deprotection of cyclic as well as acyclic O-isopropylidene sugar acetals derived from D-glucose, D-xylose, D-mannose, and D-mannitol in aqueous MeOH at room temperature. A notable observation is the conversion Of D-mannitol triacetonide into 1,2:3,4-di-O-isopropylidene-D-mannitol (48%) and 3,4-O-isopropylidene-D-mannitol (36%) brought about in 6 h by H-beta zeolite and the non-occurrence of any hydrolysis in the case of H-ZSM-5 catalyzed reaction in 24 h under the same conditions. (c) 2008 Elsevier Ltd. All rights reserved.

引用

页码：1801 / 1807

页数：7

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