Selective deprotection of terminal isopropylidene acetals and trityl ethers using HClO4 supported on silica gel

被引：59

作者：

Agarwal, A ^{[1
]}

Vankar, YD ^{[1
]}

机构：

[1] Indian Inst Technol, Dept Chem, Kanpur 208016, Uttar Pradesh, India

来源：

CARBOHYDRATE RESEARCH | 2005年 / 340卷 / 09期

关键词：

isopropylidene acetals; trityl ether; HClO4-SiO2;

D O I：

10.1016/j.carres.2005.04.005

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Terminal isopropylidene acetals are selectively cleaved to the corresponding 1,2-diols in good to excellent yields in 6-24 h at room temperature by using the 'HClo(4)(.)SiO(2)' reagent system. Likewise, trityl ethers are readily cleaved to the corresponding alcohols in good to excellent yields within 2-3 h at room temperature. Work-up involves merely filtration of the reagent followed by purification of the crude product. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：1661 / 1667

页数：7

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