Elastin as a biomaterial for tissue engineering

被引：362

作者：

Daamen, W. F.

Veerkamp, J. H.

van Hest, J. C. M.

van Kuppevelt, T. H.

机构：

[1] Radboud Univ Nijmegen Med Ctr, NCMLS, Dept Biochem 280, NL-6500 HB Nijmegen, Netherlands

[2] Radboud Univ Nijmegen Med Ctr, Fac Sci, Dept Organ Chem, NL-6500 HB Nijmegen, Netherlands

来源：

BIOMATERIALS | 2007年 / 28卷 / 30期

关键词：

elastin; elastic fibre; biomaterial; review;

D O I：

10.1016/j.biomaterials.2007.06.025

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Biomaterials based upon elastin and elastin-derived molecules are increasingly investigated for their application in tissue engineering. This interest is fuelled by the remarkable properties of this structural protein, such as elasticity, self-assembly, long-term stability, and biological activity. Elastin can be applied in biomaterials in various forms, including insoluble elastin fibres, hydrolysed soluble elastin, recombinant tropoelastin (fragments), repeats of synthetic peptide sequences and as block copolymers of elastin, possibly in combination with other (bio)polymers. In this review, the properties of various elastin-based materials will be discussed, and their current and future applications evaluated. (c) 2007 Elsevier Ltd. All rights reserved.

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收藏

页码：4378 / 4398

页数：21

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