In vivo antithrombotic effects of a nitric oxide-releasing aspirin derivative, NCX-4016

被引：88

作者：

Wallace, JL

Muscara, MN

McKnight, W

Dicay, M

Del Soldato, P

Cirino, G

机构：

[1] Univ Calgary, Dept Pharmacol & Therapeut, Calgary, AB T2N 4N1, Canada

[2] NicOx SA, Paris, France

[3] Univ Naples Federico II, Dept Expt Pharmacol, Naples, Italy

来源：

THROMBOSIS RESEARCH | 1999年 / 93卷 / 01期

关键词：

nitric oxide; platelet; ulcer; thrombosis; thromboxane;

D O I：

10.1016/S0049-3848(98)00134-0

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

[No abstract available]

引用

页码：43 / 50

页数：8

共 24 条

[11] Simultaneous determination of nitrite and nitrate anions in plasma, urine and cell culture supernatants by high-performance liquid chromatography with post-column reactions [J].

Muscara, MN ;

deNucci, G .

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 1996, 686 (02) :157-164

[12] ANTI-THROMBOTIC EFFECT OF VERY LOW-DOSES OF ACETYL SALICYLIC-ACID IN RATS [J].

PARIS, J ;

FOURNAU, P ;

GRANERO, M ;

VIENS, C .

THROMBOSIS RESEARCH, 1983, 29 (03) :313-321

[13]

PATRONO C, 1994, NEW ENGL J MED, V330, P1287

[14] LOW-DOSE ASPIRIN AND INHIBITION OF THROMBOXANE B-2 PRODUCTION IN HEALTHY-SUBJECTS [J].

PATRONO, C ;

CIABATTONI, G ;

PINCA, E ;

PUGLIESE, F ;

CASTRUCCI, G ;

DESALVO, A ;

SATTA, MA ;

PESKAR, BA .

THROMBOSIS RESEARCH, 1980, 17 (3-4) :317-327

[15] FAILURE OF ASPIRIN AT DIFFERENT DOSES TO MODIFY EXPERIMENTAL THROMBOSIS IN RATS [J].

REYERS, I ;

MUSSONI, L ;

DONATI, MB ;

DEGAETANO, G .

THROMBOSIS RESEARCH, 1980, 18 (05) :669-674

[16] ACETYLATION OF PROSTAGLANDIN SYNTHASE BY ASPIRIN [J].

ROTH, GJ ;

STANFORD, N ;

MAJERUS, PW .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1975, 72 (08) :3073-3076

[17] Effects of NO-releasing aspirin on functional and mucosal ulcerogenic responses in the rat stomach: Comparison with aspirin. [J].

Ukawa, H ;

Tanaka, A ;

Yamamoto, H ;

Nishijima, M ;

Takeuchi, K .

GASTROENTEROLOGY, 1998, 114 (04) :A314-A315

[18]

Ukawa H, 1997, GASTROENTEROLOGY, V112, pA317

[19] Reduction of shock-induced gastric damage by a nitric oxide-releasing aspirin derivative: role of neutrophils [J].

Wallace, JL ;

McKnight, W ;

Wilson, TL ;

Del Soldato, P ;

Cirino, G .

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 1997, 273 (06) :G1246-G1251

[20] Anti-thrombotic effects of a nitric oxide-releasing, gastric-sparing aspirin derivative [J].

Wallace, JL ;

McKnight, W ;

DelSoldato, P ;

Baydoun, AR ;

Cirino, G .

JOURNAL OF CLINICAL INVESTIGATION, 1995, 96 (06) :2711-2718

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